Workshop 5: Infrastructure and Methods in Patient Centered Outcomes Research

The 5th Workshop on Quantitative Methods in Education, Health and the Social Sciences (QMEHSS) will be on Friday March 7th from 11:00-12:30 and will be led by Dr. David Meltzer. The seminar will be held in the NORC conference room 344. NORC is located at 1155 E. 60th Street.


Infrastructure and Methods in Patient Centered Outcomes Research

David Meltzer MD, PhD

University of Chicago

Patient centered outcomes research (PCOR) has emerged as a new entity within clinical and outcomes research in the United States but has much in common with prior research in these areas.     This talk will review the motivation and policy context for the growth of PCOR with an emphasis on methods that are purported to differentiate PCOR from prior research in these areas, including methods to assess treatment effect heterogeneity and to analyze observational data.  Three examples will be used to frame the discussion: a randomized trial underway to examine the effects of provider in the doctor patient relationship on patient costs and outcomes,  a randomized clinical trial being designed to test the effect of alternative transfusion strategies on patient outcomes, and an observational study that attempts to measures the effect of hospital length of stay on readmissions rates using a novel instrumental variable.  All examples draw to some extent on new clinical research infrastructure created to support PCOR, including the recently funded Chicago Area Patient Centered Outcomes Research Network (CAPriCORN), and all illustrate  methodological challenges that will be critical to increasing the impact of PCOR.